Zenflore launch - Our first probiotic for stress, targeting the gut-brain axis.

PrecisionBiotics launches new Zenflore®supplement based on the science of the gut brain-axis. 


PrecisionBiotics has just launched Zenflore® in Ireland, available in pharmacies and healthfood stores nationwide. The  special 1714-Serenitas™ culture in Zenflore® has been clinically studied in people with everyday stress and has been shown to impact the level of the stress hormone, cortisol**. Combining this unique Bifidobacterium longum 1714™ culture with specially selected B vitamins, Zenflore provides helps support a healthy mind and combat stress related fatigue*.

As part of the launch, 2 of our research collaborators, Professor Ted Dinan and Professor John Cryan at the APC Microbiome Institute at University College Cork, Ireland discussed the impact of the gut-brain axis with national press and radio channels.

Ted Dinan is a Professor of Psychiatry at UCC. His primary research focus is on the role of gut microbiota in influencing brain function and development. John Cryan is Professor & Chair of the Department of Anatomy & Neuroscience at UCC. His research is focused on understanding the interaction between the brain, gut and microbiome, and how it applies to stress, mood and immune-related disorders. He has edited three books including “Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease” and has also presented a TED talk on the subject. 

Their work has shown that there is a direct connection between the brain and the gut. There is a gut-brain axis which allows a two-way dialogue between the brain and the gut. This allows co-ordination of brain and gut functions, by transmitting information from the gut to the brain, and the brain to the gut. The vagus nerve is a key physical link that relays the information between the two and it is the largest nerve in the body outside of the spinal cord.

The gut produces 90% of the serotonin found in the body and scientists have found that the gut's bacteria and microflora can influence its production. Serotonin is a neurotransmitter, a chemical messenger, known to affect a person’s mood and feelings of happiness and pleasure. Discoveries like this highlighting the critical influence of the gut microbiota outside of the gastrointestinal tract let to research that ultimately resulted in the development of Zenflore.


*Biotin, Folate, Niacin, Thiamine, B6, B12: contributes to normal psychological function. Folate, Niacin, Pantothenic Acid, Riboflavin, B6 and B12: contributes to reduction in tiredness and fatigue.

**Bifidobacterium longum 1714 as a translational psychobiotic: modulation of stress, electrophysiology and neurocognitive in healthy volunteers. Allen et al., Transl Psychiatry, 2016